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Health & Disease

All about cholesterol

The latest science on how blood levels of HDL, LDL and more relate to cardiovascular health

CRISPR gene editing: Moving closer to home

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot going on in the genome editing field. Here’s our primer.

Genes and heart disease: Finally making the link

Polygenic risk scores — a patient’s chance, based on tiny DNA variants, of developing cardiovascular disease, breast cancer and more — are coming to clinics. But there are kinks to iron out and accuracy remains an issue.

Scientists scrutinize happiness research

From meditation to smiling, researchers take a second look at studies claiming to reveal what makes us happy

Salt taste is surprisingly mysterious

Too much sodium is bad, but so is too little — no wonder the body has two sensing mechanisms

The neurons that make us feel hangry

Neuroscientists think a cluster of cells in the brain that stimulate appetite could be a target for eating disorder therapies

Amyloidosis: Beyond Alzheimer’s and Parkinson’s

Amyloid plaque can build up in body organs other than the brain. The resulting diseases — AL amyloidosis, ATTR amyloidosis and more — cause much suffering.

Covid, RSV and the flu: A case of viral interference?

The ‘tripledemic’ unfolding this winter is one of several odd trends among respiratory virus infections these last years. Viruses, it turns out, can block one another and take turns to dominate.

Could getting rid of old cells turn back the clock on aging?

Researchers are investigating medicines that selectively kill decrepit cells to promote healthy aging — but more work is needed before declaring them a fountain of youth

Sex, immunity and the brain

Differences between the immune systems of males and females — in particular, ones involving cells called microglia — might help explain why the risk for conditions such as autism and Alzheimer’s varies between the sexes

Fun facts about bones: More than just scaffolding

A new vision of the skeleton as a dynamic organ that sends and receives messages suggests potential therapies for osteoporosis and other problems

Know thine enemy: Why genetic sequencing is key to tracking Covid-19

The US effort to analyze viral genomes, slow to start, is now picking up speed

Friendly fire: How autoantibodies could drive severe Covid

Some serious cases of Covid-19 are linked with the immune system’s attack on the body it’s trying to protect

The challenges of antiviral treatments

Antibiotics abound, but virus-fighting drugs are harder to come by, and Covid-19 amply shows how much we need them. Fortunately, scientists are getting better at making and finding them.

I got the Pfizer Covid-19 vaccine. Or maybe not.

OPINION: Many Americans say they won’t take a vaccine. I am not one of <br xmlns="http://pub2web.metastore.ingenta.com/ns/"/>them — and I have the shots to prove it.

Viruses that come to stay

Some linger in the body for a lifetime. The one causing Covid-19 probably isn’t one of them, but it and others can create mischief long after the immune system appears to have banished them.

Rodents in space: Keeping bone and muscle strong on the ISS

Researchers helped mice stay mighty with an experiment to counter the effects of microgravity. The gene treatment might also enhance muscle and bone health on Earth — and in humans.

Blood clots: A major problem in severe Covid-19

Out-of-control clotting can endanger some patients even after the virus has gone. Clinicians and researchers are trying to understand why it happens and how best to manage the problem.

Making and breaking connections in the brain

The links between nerve cells, called synapses, allow us to learn and adapt, and hold clues to conditions such as autism, schizophrenia and more

Mini-organs push along Covid-19 and other virus research

While studies in mice and people can be slow, researchers are making fast progress testing medications in miniature airways and guts made of human cells

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