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Health & Disease

Scientists scrutinize happiness research

From meditation to smiling, researchers take a second look at studies claiming to reveal what makes us happy

Top science stories of 2023

Twelve standout news events and trends in a tumultuous year

Untangling the genetics that underlie our facial features

After turning up hundreds of genes with hard-to-predict effects, some scientists are now probing the grander developmental processes that shape face geometry

The remaining frontiers in fighting hepatitis C

A scientist whose work was key to identifying, studying and finding treatments for this life-threatening virus discusses the scientific journey and challenges that persist

New devices could change the way we measure blood pressure

Embedded in a cell phone or in accessories such as rings, bracelets or watches, the novel tools aim to make it easier to manage hypertension. But they must still pass several tests before hitting the clinic.

How climate change could make fungal diseases worse

Disease-causing fungi are likely to thrive in a warmer, stormier world — and more of them might be poised to make the leap to infecting people

Salt taste is surprisingly mysterious

Too much sodium is bad, but so is too little — no wonder the body has two sensing mechanisms

How optimizing indoor humidity can help stop the spread of Covid and flu

OPINION: Recent CDC guidelines for indoor air quality disregard the benefits of humidity. But research shows it can kill viruses and help thwart infections.

New noninvasive RNA tests could help identify at-risk pregnancies

The next wave of prenatal screening looks for fragments of RNA within the blood to flag risk of preeclampsia and preterm labor

Rapid experiments to improve health-care delivery

Public health experts are borrowing a technique from the tech world to make messaging more effective — so that patients are more likely to get preventive care

Preparing for future pandemics: Learning from Covid-19

VIDEO: Knowable Magazine’s interviews with experts during the pandemic revealed many missed opportunities and blunders in the US response to Covid-19, which was marked by excess American deaths and disability. The experience does offer lessons on how to better prepare for what scientists call the inevitable emergence of the next global health emergency.

Medications for opioid use disorder — MOUD — and adolescents

Treatment with drugs such as buprenorphine, methadone and naltrexone is deemed the gold standard for youth with opioid addictions. Why isn’t it used more often?

New views of a cough: From TB and chronic cough to hope for Parkinson’s

Scientists are revealing new secrets of the reflex that protects our lungs, spreads disease and irritates us all

How the placebo effect went mainstream

PODCAST: Sloppy by today’s standards, and maybe even back when it was published in 1955, Henry Beecher’s paper paved the way for sounder drug trials and pushed scientists to better understand how we process pain (Season 3, Episode 3)

Dealing with rats, and their health, in America’s ‘rattiest’ city

OPINION: A study in Chicago found that rodents surviving poisoning are more likely to carry disease. Good pest control needs to take such things into account.

The neurons that make us feel hangry

Neuroscientists think a cluster of cells in the brain that stimulate appetite could be a target for eating disorder therapies

Reading the mind with machines

Researchers are developing brain-computer interfaces that would enable communication for people with locked-in syndrome and other conditions that render them unable to speak

What if we tolerated diseases?

The immune cells that fight bacteria and viruses are well-known. But some scientists think we should devote more attention to a second prong of defense: one that allows our bodies to more harmlessly live with pathogens until they’re cleared from our systems.

Hope for haploinsufficiency diseases

Genetic conditions like Dravet syndrome, which causes severe childhood epilepsy, are hard to tackle with traditional gene therapy. New approaches in the works include using antisense therapy to boost mRNA splicing.

Amyloidosis: Beyond Alzheimer’s and Parkinson’s

Amyloid plaque can build up in body organs other than the brain. The resulting diseases — AL amyloidosis, ATTR amyloidosis and more — cause much suffering.

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